Psoriasis Clinical Presentation And Epidemiology

Erythrodermic psoriasis presents as an intense, bright-red, inflmmatory dermatitisinvolving at least 75% of the body surface area (Figure 17.1) [10]. It is rare, with an estimated prevalence of 1%–2.25% among psoriasis patients, and can occur de novo or in patients with preexisting psoriasis [11]. Patients may appear ill—with fever, chills, and malaise [11]. The course of erythrodermic psoriasis varies from acute and rapidly progressive to prolonged and chronic, which may follow a relapsing–remitting pattern.

Psoriasis is the most common cause of erythroderma and represents about 25% of cases.
Other causes of erythroderma include cutaneous lymphoma, pityriasis rubra pilaris, severe
eczema, and drug eruptions [12–14]. Ths, biopsy may be useful in distinguishing erythrodermic psoriasis from these other causes of erythroderma.

Pustular psoriasis has been historically classifid into two forms: localized and generalized.
Generalized pustular psoriasis can be further divided based on the acuity of presentation
and natural history of disease. Annular pustular psoriasis usually follows a chronic, more
benign course. In contrast, the von Zumbusch type is oftn a more severe presentation, characterized by the rapid onset of widespread sterile pustules on a background of erythema
(Figure 17.2) [15]. Like erythrodermic psoriasis, preexisting psoriasis vulgaris may or may
not be present [16]. Initially, pustules may be located at the periphery of psoriatic plaques,
where inflmmation is the most active. However, once the disease becomes generalized, it
can develop on any involved skin [17]. Conflence of these pustules may form irregular
“lakes of pus” over part or all of the body. Th patient may appear toxic, with fever, chills,
pain, and intense pruritus [18]. Other possible fidings include a geographic or fisured
tongue, scaly lips with superfiial ulcerations, and ocular involvement (e.g., conjunctivitis,
uveitis, or iritis).
Psoriasis Clinical Presentation And Epidemiology Psoriasis Clinical Presentation And Epidemiology Reviewed by anti psoriasis on 2:40 PM Rating: 5
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